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1984 Sexual Rebellion
Jamie Aragon English 12 B-2 17 March 2005 Sexual Rebellion The First Lady, Abigail Adams, when expressed, ââ¬Å"If specific considerat...
Saturday, November 9, 2019
How to Change Your Oil
Michael Marcel Informative Speech Outline Topic: Changing engine oil Specific Purpose: To inform my audience about the three steps to changing their engine oil. Central Idea: The three steps in changing engine oil are gathering the necessary supplies, draining and filling the oil, and safely disposing of the oil. Introduction l. Have you ever been stranded on the side of the road? It's never a good thing. Keeping up with your vehicle maintenance is a very important element. According to the car research website Edmunds. Com states the majority of automakers call for oil hangers at either 7,500 or 10,000 miles.II. Vehicle repairs are getting more expensive by the year. Preventative maintenance will definitely cut back on those costs for you. Ill. I personally have been changing the oil in my truck at every 3,000 to 4,000 miles since I was sixteen years old. IV. Today I would like to inform you of the three major steps in changing your engine oil, which are gathering the necessary supp lies, draining and filling the oil, and safely disposing of the oil. Transition: Let's start with gathering the supplies for your oil change. Body l. Before actually beginning the oil change there are a few things to take care of.A. Find out and purchase the right amount of oil for your vehicle. B. Buy a new oil filter for the make and model of your vehicle. C. You will need a drain pan, a wrench for the oil drain plug, and possibly an oil filter wrench depending on how tight your filter is. Transition: Now that we know the necessary supplies to change your oil, let's talk about removing and replacing the old oil. II. There are four steps to follow for taking the used oil out of your car and replacing it. A. Place the drain pan under your car and remove the old oil filter. B.Loosen the oil drain plug with the normal wrench and let the oil drain into your pan. C. Replace the drain plug and install the new filter. D. You can now fill the oil back to your cars specifications from under the hood. Transition: Now that your oil is changed there are still a few steps left. Ill. In the U. S. , the California recycling website states less than 60 percent of used oil is recycled. Now it is time to dispose of your used oil. A. You should avoid prolonged contact with the used oil. Used oil can contain toxic substances such as benzene, lead, zinc, and cadmium. B.Always be aware of the temperature of the oil you're handling. C. Most local auto shops have an oil-recycling center. It is also important to recycle the filter. Recycle-steel. Org states that if all the filters sold across the U. S. Annually were recycled we would recover roughly 160,000 tons of steel. That's enough steel to build sixteen new stadiums the size of Atlanta's Turner Field. Conclusion l. In conclusion today I have told you the three steps to changing your oil, which are adhering the necessary supplies, draining and filling the oil, and safely disposing of the oil.II. I hope this has inspired you to st art saving a little time and money by changing your own oil.
Thursday, November 7, 2019
The Planning Process Example
The Planning Process Example The Planning Process ââ¬â Article Example International Planning Process Task: Planning Process In the planning process, Phases II and I mainly center on sorting out. Mostly, a country that lacks reasonable potentials for advanced analysis is purged. Phase I accesses suitability of the Country by considering environmental factors and countryââ¬â¢s character. If the country presents an overall compromised state, it is not preferred for investment (Cateora & Graham, 2007). A country with a weak economy that avails no potential of supporting businessââ¬â¢s activities is avoided. Additionally, the country should be stable politically, and prospects should show future stability. Political instabilities affect the business and its environment hence providing a risky venture. Importantly, the countryââ¬â¢s resources and industrial state should sustain the project under consideration (GruÃËnig & KuÃËhn, 2005). Competition forces in the country also provide a noteworthy measure tool. Country presenting stiff competitions implies that the new launch may fail to tap sizeable market hence investor feels that an endeavor is not profitable. Countries with official legislations that may undercut the product is also not preferred. Virtually, any factor posing challenges of poor market, low profits, unhealthy competitions, compromised stability, and unendurable legislations leads to dropping of a country (Doole & Lowe, 2008). Phase II exerts a more analysis examining the adaptability of products in the Countryââ¬â¢s market. The stage surveys the cultural environment essential for the establishment of the product and dissects if probable cost is sustainable. The nature provided by the products should be acceptable in the country (Doole & Lowe, 2008). This means productââ¬â¢s adaptation, packaging, branding and warranty need to blend with countryââ¬â¢s state. In addition, distributions requirements like logistics and feeds should satisfy the study criteria to ensure penetration and distribution of t he product. Lastly, facilities for fueling promotions need be accessible to enhance the productââ¬â¢s campaign. Failing to satisfy these conditions may lead to Countryââ¬â¢s dismissal in Phase II. ReferencesCateora, P. R., & Graham, J. L. (2007). International marketing. Boston, Mass: McGraw-Hill.Doole, I., & Lowe, R. (2008). International marketing strategy: Analysis, development and implementation. London etc.: South Western Cengage Learning.GruÃËnig, R., & KuÃËhn, R. (2005). Process based strategic planning. Berlin [u.a.: Springer.
Tuesday, November 5, 2019
What Does the End of Summer Mean to You
What Does the End of Summer Mean to You Iââ¬â¢m taking a non-traditional approach to my blog this week because Iââ¬â¢m feeling reflective.à Tomorrow I head out of town for a final vacation on the East Coast (New Hampshire).à Iââ¬â¢m going to Dance New Englandââ¬â¢s summer dance camp, a place I have spent from four to eleven days every year (except one) for the past twelve years. It has become automatic for me that the end of summer means Iââ¬â¢m heading to dance camp.à In fact, I almost didnââ¬â¢t go to camp this year because I had so much work to do, engagements on my calendar, etc.à But this ritual of camp is so ingrained that a week ago I cancelled all my appointments and bought a plane ticket.à The end of summer just isnââ¬â¢t the same without dance camp. The end of summer also means fall colors coming, and crispness in the air.à Apples flooding the farmers market where berries used to be.à Thoughts of snow shovels encroaching. Most important, however (yes even more important than dance camp), the end of summer means admissions season is approaching, and life is about to get even busier for The Essay Expert.à For the past nine months I have been a resume writer and business owner, as well as a career advisor at the University of Wisconsin Law School.à In a few short weeks, ââ¬Å"College Admissions Essay Advisorâ⬠will move to the top of the list along with ââ¬Å"Law School Admissions Consultantâ⬠for Kaplan. I look forward to this upcoming time of year.à College and law school applicants all have unique stories to tell, and I love learning and exploring them.à I love working with students, helping them gain insights into their lives that they might not have had otherwise.à I love watching peopleââ¬â¢s stories reveal themselves onto the page in a way that captures the interest of admissions officers because no one else could have told those stories in that particular way. And of course I love helping clients get into the colleges and law schools of their choice. I associate apples and fall crispness, even Thanksgiving, with the process of shepherding students into their next phase of life.à Itââ¬â¢s a rewarding venture and the results will flower with the spring.à In the meantime, Iââ¬â¢m heading to dance camp.à Iââ¬â¢ll have more bloggery for you when I get back. Iââ¬â¢m curiousâ⬠¦Ã what does the approach of the end of summer mean to you?à Are you a job seeker getting ready to buckle down in your search?à Are you the parent of a high school senior getting ready to increase your encouragement for your child to write an essay draft?à Are you a teacher writing letters of recommendation?à Please share in the comments below. Save Category:College AdmissionsBy Brenda BernsteinAugust 18, 2010 8 Comments Ellen Ingraham says: August 20, 2010 at 7:32 am My summers as an adult are so different than when I was a child. Every summer until I was twelve was spent at my grandmothers house down the Jersey shore. Days were filled with the beach, tennis and swim teams. The same kids came every year, and so did their parents and in most cases, their grandparents. No contest, it is my best childhood memory. Now I prepare for my son to start high school, my daughter to start her sophomore year at college. We spenta day at the Jersey shore this week, and I amazed the teenagers how this 53 year old could body surf! The water was cold and rough with huge waves I felt like a kid again. I look forward to growing my business this year, making new friends online, and enjoying the beautiful area that we live in. The Delaware river reaplces the Atlantic Ocean as the close-by water source. Although I kow my chidlren will have thier own memories about summer here, I do wish I could give them what I had. Not only the beach, but the community of multigenerational families; growing up knowing my friends Moms, and their Grandmas. Have fun at dance camp! Ellen Log in to Reply Diane Kern says: August 24, 2010 at 1:16 pm Dance Camp-that is a worthy ritual. I love the fall,but Im not ready for it yet. A Wisconsin native and recent transplant from Maine to Washington, fall is October,pumpkin festivals, and leaf peeping. A very short fall posting from me. https://wp.me/pohHp-b4 Log in to Reply Chris Paulsen says: August 24, 2010 at 1:18 pm This fall brings the senior year for our youngest son. The older siblings are already off to college. Weve been transitioning to parenting adults for several years now. Just one year left. Log in to Reply Jessica Oman says: August 30, 2010 at 3:27 pm For me, the end of the summer always brings excitement. Ive worked in post-secondary education for many years and I always enjoy the buzz of students returning to school, cracking open new textbooks, meeting new instructors. While many people associate the Spring with new beginnings, for me that fresh start has always come in September. I always look forward to this time of year to new projects, new connections, and new clients! Log in to Reply Rosanne Dingli says: September 6, 2010 at 9:16 am I live in Australia, so we are the other way around. Our Winter has just ended, and Spring is in the air. We did not get quite enough rain this winter, and the garden needs it, so heres hoping we get a wet Spring. All you guys in the US enjoy your Fall. Rosanne Dingli author of puzzle thrillers https://rosannedingli.blogspot.com Log in to Reply Mari-Lyn says: September 14, 2010 at 2:15 pm The end of summer ended with a 5,000 mile road trip of which, I really enjoyed..it felt like I had a summer.. I always like going to summer camp as a kid,,I always had fun it wish there was a summer camp for adults so we can re-live our childhood or do it again. Mair-Lyn Log in to Reply Teresa says: April 5, 2012 at 1:56 am Nice to hear that someone has a good attitude about summers end. Fall truly is glorious. Thanks for the lovely post! Log in to Reply Scott says: January 15, 2014 at 10:30 am The end of summer really can happen at anytime, its the end of those warm feelings of excitement. It can be meeting someone that takes your breath away, a life adventure that has new experiences and joy like your havent imagined with other people or the smallest things of taking someone to the airport very early when you have trouble getting up in the morning. This time is about how life is dying on the vine, where your dreams pass by, coldness is in the air and closeness escapes you. Profound sadness that time has passed you by. Your expressions go back into a shell for protection, they may come out again, but not in the same way. The warmth that was there is gone. Log in to Reply
Sunday, November 3, 2019
Ethics of educational leadership Essay Example | Topics and Well Written Essays - 1250 words
Ethics of educational leadership - Essay Example These aspects will be critical in enabling me to lead a happy life. In addition, I will be able to impact on other people through sharing my experiences with others and giving a helping hand where necessary. My second code of ethics is respect for humanity, regardless of the differences. Currently, the world has become very dynamic with each challenges arising each day (Beckner, 2004). As a result, interaction with people from diverse cultures, religions, races, and gender has become a critical aspect towards achieving personal objectives. On the other hand, organizations are employing subordinates that emanate from different parts of the world (Howard, & Korver, 2008). This is to enable them to tackle various challenges. As a result, this personal code of ethics is significant in enabling me to interact with people and understand their ways of doing things. This enables me to appreciate diversity and learn how to live with people from various parts of the world. Decision making is a process that requires a procedure. While making a critical decision, I first recognize the ethical issue that need to be observed. This is through analyzing whether the decision could affect a person or a group of people. In addition, I balance between the benefits and damages that are likely to be brought by this decision. Then, I analyze the legality of the decision and whether itââ¬â¢s the best among the alternative. The second step involves getting all the facts about the decision being made. This step identifies all the relevant steps and whether there is a need to conduct more research about the situation. I also test whether I have enough knowledge to enable me to make the appropriate decision. Furthermore, during this case, I identify all the groups that are likely to be affected by the decision either positively or negatively. Lastly, I analyze all options of acting and the person that can be consulted. The third step involves evaluating the alternative
Thursday, October 31, 2019
Team goal and team member characteristics Essay Example | Topics and Well Written Essays - 500 words
Team goal and team member characteristics - Essay Example From a psychological and moral perspective, individualism is the concept that people should think, act and judge things autonomously following their conscience. As members of the British Triathlon team, they have an obligation to fulfill. This obligation needs team members to offer high level of individual independence and accountability and providing them with a chance to follow their initiative and desire. Individualism comes with personal responsibility. The three members of the British Triathlon team have demonstrated the art of being responsible. Personal responsibility shows ones wisdom and maturity. Having the right attitude helps in avoiding the creation of unnecessary problems in life. There are situations when difficulties happen out of oneââ¬â¢s control. Sometimes, this is usually unavoidable but with personal responsibility, one is likely to optimistically pounce back and respond (Pritchett 33). Teamwork is evident in the British Triathlon team in that members interact freely and share their experiences about the game. They have established a productive environment, which allows team members development of interpersonal skills that fosters partnership and collaboration rather than rivalry and competition. Diversity in the British Triathlon comes into play when people from different backgrounds in terms of culture and skills are in the same working environment. Diversity will encompass gender, race, ethnicity, age, personality, and educational background. The British Triathlon team took advantage of diversity by incorporating their coach Malcolm Brown. This has enabled them to achieve cohesive in the workplace and achieve set goals. Alistair and Jonathan embraced diversity in the sense that since Malcolm Brown was introduced as a coach; they have cooperated and worked as a team in order to meet their goals. To ensure Smooth Corporation of team members, they have
Tuesday, October 29, 2019
Firm Fixed Price Contract for Reno Municipality to outsource Essay
Firm Fixed Price Contract for Reno Municipality to outsource remittance operations for payment processing functions - Essay Example The agency shall also be in charge of customer service center and it should be equipped with a live customer phone number and interactive internet site for enabling the customer to request for service, bill questions, and provide solutions to issues that occur like emergencies. The customer center should operate for 24 hours having at least one personnel all the time. In case of emergency the customer service should have communicated directly to the municipality. The agency should ensure that the bill is provided to the customer within two working days after getting the billing data from the municipality. The agency should also give the municipality a payment verification at the last day of reporting phase. The reporting cycle is based on the calendar days, the first day will be the date that the municipality will provide the data. Based on the delivery, the agency will be in charge of reconciling all the account billings on a monthly basis and give proper reports to the municipality. The report should contain the number of financial transactions throughout the week and the amounts of currency they represent. Including this information, is the list of computer hardware and software that is used to process the products of the municipality. The contractual terms will be on a yearly basis and renewable up to five years but the municipality retains the right not to renew after the second year if the terms are breached. The agency is entitled to a 2% of the total revenue as a compensation for their services. The low performance of the agency will be penalized on up to 25% of their fee, including other professional misconduct. Excellent performance will receive an extra 2%of the gross revenue or a lump sum bonus of about fifty thousand dollars to be decided by the company. The preparation for the proposal shall involve bids in sealed envelopes or packages which are addressed to the specific office
Sunday, October 27, 2019
The virulence factors of staphylococcus aureus
The virulence factors of staphylococcus aureus Staphylococcus aureus is faculatively anaerobic, catalase-positive, coagulase-positive, gram-positive cocci. It is non sporulating, non motile and non capsulated bacteria. 30% of Staphylococcus aureus can be found in skin, mucous of membrane and nasal passages in a healthy person as normal flora. However, Staphylococcus aureus infections are capable of leading to meningitis, pneumonia, osteomyetilis, spectic arthritis and septicemia. It is also difficult to treat Staphylococcus aureus infections if it is a methicillin resistant strain as the only antibiotic, vancomycin, is able to inhibit methicillin resistant Staphylococcus aureus(MRSA). Virulence Factors Virulence factors from Staphylococcus aureus can be structural or secreted products that lead to pathogenesis. They are classified into catogeries such as surface proteins, secreting toxins and superantigen toxin. Surface proteins in Staphylococcus aureus provide attachments to host tissues which will colonize and lead to infections. Such proteins are protein A/B which binds to immunoglobulin G, clumping factor A and B to help adherence to bacterial cells. [Plata, Rosato et al. 2009] Alpha-heamolysin, beta-heamolysin, gamma-heamolysin and Panton Valentine Leucocidine (PVL) are examples of secreting toxins which form pores in the host membrane and lyses the cells while staphylococcus enterotoxins weaken the host immune system and toxic shock syndrome toxin 1 causes toxic shock by food poisoning. These virulence factors that are produced [Plata, Rosato et al. 2009] by Staphylococcus aureus and often cause life-threatening diseases. These factors overcome and disguise themselves from th e body immune system so that Staphylococcus aureus can colonize and bind to connective tissues which lead to infections. They are also responsible for the symptoms of the disease. The main diagnostic features can be detected by having coagulase agglutination tests and test for the production of thermostable nuclease which break down DNA. [Greenwood, Slack et al. 2007] Exotoxins (TSST1-toxic shock syndrome toxin 1) TSST1 are one of the virulence factors that cause a variety of diseases in humans. TSST1 has short N-terminal à ± helix which lead to à ² barrel structure also known as B domain or oligosaccharide binding. It is then connected to C-terminal wall of the à ² strands (Domain A). This structure cause cysteine loop which result in emetic activity. If there is no loop, TSST1 will be superantigenic [Orwin, Fitzgerald et al. May 2003]. As Staphylococcus aureus invade the body, TSST1 is produced in the bacteria and release to host. It then inhibits host immune responses. It crosses mucosal surfaces and reactivates bacterial cell wall induced arthritis. [Diages, Orwin et al. Jan 2000] TSST1 also stimulate proliferation of T cells. These T cells will not only increase its concentration in the body, but they are also unable to recognize specific antigen in the bacterial cells. Subsequently, T cells cannot eradicate Staphylococcus aureus. Therefore, TSST1 is also known as superantigenicity, py rogenicity and boost the lethality of the toxins. Acquired heart disease in children is often associated with TSST1. Also, TSST1 is linked to women who use tampons regularly as it increases the exposure to Staphylococcus aureus infections. TSST1 helps to release massive amount of cytokines which results in fever, rash, low blood pressure, tissue damage and shock. [Dermnet.org] Exotoxins (Panton Valentine Leucocidin-PVL) Panton Valentine Leucidin (PVL) is usually found in community-acquired Staphylococcus aureus (CA-MRSA). Tristan (2007) stated that it is categorized as bicomponent synergohymenotropic toxin which lyses host cell membrance and it targets on human polymorphonuclear neutrophils (PMN), monocytes and macrophages. Plasma membrane of myeloid cells form octamer pores and target leukocytes by Panton Valentine Leucidin [Kobayashi and Deleo 2009]. Inflammatory mediators such as leukotriene B4, IL-8 and histamine are released to the cell surrounding as PVL activates Ca2+ channels to open leading to calcium influx in PMN, monocytes and macrophages. As long as Ca2+ channels are opened and inflammatory mediators concentration is greatly rising, it is a fatal outcome. Thus, neutrophils, monocytes and macrophages lyses as pores form in their cell membranes and this usually results in toxic shock or refractory hypoxemia. Panton Valentine Leucidin plays a major role in severe necrotizing fasciitis, pne umonia, leukocyte destruction and tissue necrosis. [Libert, Batjom et al. Jan 2009] Staphylococcus enterotoxins-SE Staphylococcus enterotoxins are the common cause of food poisoning. As individual digests a large amount of Staphylococcus aureusthrough contaminated water or food, enterotoxins are produced. It has a major cross linking with major histocompability complex (MHC) class II antigen and T cell receptor (TCR) [Fraser and Proft 2008]. T cell receptor will recruit neutrophils and release a wide variety of inflammation mediators to the stomach and small intestine. Accumulation of inflammation mediators results in hyperemic mucosa and crypt extension develops in jejunum. The disruption of the lining of the small intestine influences the rate of absorption of substances. Thus, gastroenteritis forms and will bring about the systemic symptoms such as fever and hypotension.[ Diages, Orwin et al. Jan 2000]. Vomiting and diarrhea is also a common symptom in SE food poisoning. Food poisoning by Staphylococcus aureusis less severe than other infections by the same species. It is often self limiting a s well. [Diages, Orwin et al. Jan 2000] Protein A Protein A is characterized as a cell wall associated monomeric protein. [Gomez, Lee et al. 2004]. It has role in causing pneumonia by targeting polymorphonuclear (PMN) cell migration in the airway passages. Protein A binds to the Fc region of immunoglobulin G (IgG) and causes opsonization. [Greenwood, Slack et al. 2007]. It also phosphorylates mitogen activated protein kinases (MAPKs) as pro-inflammatory signaling. IL-8 is made and secreted out from epithelial cells. In addition, protein A also mimics TNF-à ± (tumour necrosis factor à ±) that will bind to TNFR1, which is distributed at airways (tumour necrosis factor receptor 1). This will recruit TRADD (TNFR1 associated death domain protein) and TRAF2 (TNF receptor associated factor 2). Both will be activated, protein A and TRAF2 with RIP1 will coimmunoprecipitate in the airways [Gomez, Lee et al. 2004]. Furthermore, protein A inhibits phagocytic engulfment. In the same paper, Gomez also stated that if Staphylococcus aureusis lacking in protein A or TNFR1, bacterial virulence will be lower and accumulation of PMN in the lung will be decrease as well. It is harmless to activate PMN as it is to protect the lung, however, when there is an increase in protein A binding to PMN, PMN is activated and enhancing the inflammatory mediators to be released in the airways. Therefore, an increase in protein A will generate a greater inflammatory response and subsequently pneumonia develops. Staphylokinase (SAK) Staphylokinase is an enzyme that produces by Staphylococcus aureus. When staphylokinase is released from Staphylococcus aureus and targeted to neutrophils, à ±-defensins is produced and followed by neutralization of short peptides by Staphylococcus aureus. This results in inhibition of bactericidal effects of defensins by the activation of plasminogen and staphylokinase increases bacterial infection process. [Bergmann and Hammerschmidt 2007] Plasminogen is tightly regulated and it is a part of fibrinolysis mechanism which coagulates fibrin when a blood vessel is injured. Staphylococcus aureus changes plasminogen to fibrin with the help of fibrin as co-factor. Staphylokinase is encoded by the Sak gene and regulated by the agr gene. Its structure has a central à ±-helix and 5 à ² sheet strands. [Bokarewa, Jin et al. 2006]. Once neutophils is bound to the central à ±-helix, it induces conformational changes. Consequently, plasminogen is converted to plasmin. Fibrin clots is then bro ken down by plasmin and kept the infection localized. Staphylokinase-plasminogen complexes also help Staphylococcus aureus to enter the host tissues. Furthermore, Maria stated that if 2 staphylokinase form a dimer due to the central à ±-helical, it will reduce antigenicity. Several binding sites to neutrophils can be found in staphylokinase. This will induced in releasing of à ±-defensins and affect the bactericidal properties as peptides are being neutralized. Staphylococcus aureusis then resistant to phagocytosis by neutrophils. [Bokarewa, Jin et al. 2006]. Staphylokinase infections are usually found in sepsis, immunocompromised and elderly patients as they are more prone to Staphylococcus aureus. Antibiotics are the usual therapy of these infections. Virulence Factors in Staphylococcus aureusare the main components that causing life threatening diseases. It is mostly the mediators released by the immune system gives the symptoms for the diseases. If there are any mutations in these virulence factors, it will be less virulent to the bacteria and the symptoms of disease will lessen as these virulence factors will not target neutrophils, macrophages and other immune system components. Therefore, inflammation mediators are not released in a great amount at once.
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